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OR = 3.1, 95% CI = 2.44.2, p-value = 0.0002) (Table 1)

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J Biol Chem, 262(36): 17690-17695

217 An RCT in Iran compared the proportion of patients with focal or generalized epilepsy achieving 50% seizure reduction between 34 patients randomized to 2 months of MAD (22 completed the study), compared to 32 patients randomized to standard medical management, and found 35.5% (12/34) efficacy in the MAD group (intention-to-treat (ITT) analysis) at 2 months compared to 0% in the control group, a difference that was statistically significant